Colored pencil drawing illustration of synaptic exocytosis in hippocampal neurons. By Tingting Wang.
Learn more in Wang et al., Cell 2012
Watercolor painting illustration of synaptic transmission. By Tingting Wang and Shan Meltzer.
Learn more in Wang et al., Cell Reports 2016
Confocal image of peripheral glia in Drosophila. By Tingting Wang.
Learn more in Yin et al., Journal of Neuroscience 2023 Cover Article, Featured Research
Publications
Cui, T., Wang, T., (2025) Exact box-counting and temporal sampling algorithms for fractal dimension estimation with applications to animal behavior analysis. Results in Engineering 2025 Mar;25:103755. PMID: 40230598 Code: Fractal
Cai, Y., Wang, T., (2024) Regulation of presynaptic homeostatic plasticity by glial signalling in Alzheimer's disease. Journal of Physiology 2024, Dec 20. PMID: 39705214
Wang, T., Frank C.A., (2024) Measuring Presynaptic Calcium Influx at the Drosophila Larval Neuromuscular Junction. Cold Spring Harb Protoc 2024, Apr 30. PMID: 38688542
Wang, T., Frank C.A., (2024) Measuring the Readily Releasable Synaptic Vesicle Pool at the Drosophila Larval Neuromuscular Junction. Cold Spring Harb Protoc 2024, Apr 30. PMID: 38688540 Code: HFRP_analysis
Wang, T., Frank C.A., (2024) Eliciting Presynaptic Homeostatic Potentiation at the Drosophila Larval Neuromuscular Junction. Cold Spring Harb Protoc 2024, Apr 30. PMID: 38688541
Wang, T., Frank C.A., (2024) Using Electrophysiology to Study Homeostatic Plasticity at the Drosophila Neuromuscular Junction. Cold Spring Harb Protoc 2024, Apr 30. PMID: 38688539
Zhang, Y., Wang, T., Cai, Y., Cui, T., Kuah, M., Vicini, S., Wang, T., (2023) Role of α2δ-3 in Regulating Calcium Channel Localization at Presynaptic Active Zones during Homeostatic Plasticity. Frontiers in Molecular Neuroscience 2023, Nov 7. 16:1253669. PMID: 38025261 Code: alphafold_view
Cai, Y., Cui, T., Yin, P., Paganelli, P.M., Vicini, S., Wang, T., (2023) Dysregulated Glial Genes in Alzheimer’s Disease Are Essential for Homeostatic Plasticity: Evidence from Integrative Epigenetic and Single Cell Analyses. Aging Cell 2023, Sep 15:e13989. PMID: 37712202
Yin, P., Cai, Y., Cui, T., Berg, A.J., Wang, T., Morency, D.T., Paganelli, P.M., Lok, C., Xue, Y., Vicini, S., Wang, T., (2023) Glial Sphingosine-mediated Epigenetic Regulation Stabilizes Synaptic Function in Drosophila Models of Alzheimer's Disease. Journal of Neuroscience 2023, Sep 5. PMID: 37669862 Cover Article, Featured Research
Cui, T., Wang, T., (2023) A Comprehensive Assessment of Hurdle and Zero-inflated Models for Single Cell RNA-sequencing Analysis. Briefings in Bioinformatics 2023, July 28. PMID: 37507115 Code: TensorZINB, CountModels, R2Jupyter
Yin, P., Xue, Y., Wang, T., Zhong, D., Li, G., (2021) The Therapeutic Targets of Fingolimod (FTY720) Are Involved in Pathological Processes in the Frontal Cortex of Alzheimer's Disease Patients: A Network Pharmacology Study. Frontiers in Aging Neuroscience 2021, Feb 2;13:609679. PMID: 33603656
Cui, T., Wang, T., (2021) JOINT for Large-scale Single-cell RNA-sequencing Analysis via Soft-clustering and Parallel Computing. BMC Genomics 2021, Jan 11;22(1):47. PMID: 33430769 Code: JOINT pdf supplemental
Wang, T., Morency, D.T., Harris, N., Davis, G.W., (2020) Epigenetic Signaling in Glia Controls Presynaptic Homeostatic Plasticity. Neuron 2020, Feb 5;105(3):491-505.e3. PMID: 31810838
Selected Publications before 2018
Hauswirth, A.G., Ford, K.J., Wang, T., Fetter, R.D., Tong A, and Davis, G.W., (2018) A Postsynaptic Signaling Platform for Retrograde, Trans-Synaptic Control of Presynaptic Homeostatic Plasticity. Elife 2018, Jan 5;7. e31535. PMID: 29303480
Wang, T., Jones, R.T., Whippen, J.M., Davis, G.W., (2016) α2δ-3 is Required for Rapid TransSynaptic Homeostatic Signaling. Cell Reports 2016, Sep 13;16(11):2875–88. PMID: 27626659
Wang, T., Hauswirth, A.G., Tong, A., Dickman, D.K., Davis, G.W., (2014) Endostatin is a Trans-Synaptic Signal for Homeostatic Synaptic Plasticity. Neuron 2014, Aug 6;83(3):616-29. PMID: 25066085
Parrish, J.Z., Kim, C.C., Tang, L., Bergquist, S., Wang, T., Derisi, J.L., Jan, L.Y., Jan, Y.N., Davis, G.W., (2014) Krüppel Mediates the Selective Rebalancing of Ion Channel Expression. Neuron 2014, May 7;82(3):537-44. PMID: 24811378
Wang, T., Hanus, C., Cui, T., Helton, T., Bourne J., Watson D., Harris, K.H., and Ehlers, M.D., (2012) Local Zones of Endoplasmic Reticulum Complexity Confine Cargo in Neuronal Dendrites. Cell 2012, Jan. 20;148(1-1):309-21. PMID: 22265418
Codes
Algorithms published by the Wang lab: https://github.com/wanglab-georgetown
Google scholar: https://scholar.google.com/citations?hl=en&user=NnYeeRcAAAAJ
Copyright © 2024 Wang Lab at Georgetown University. All Rights Reserved.